Vagus nerve stimulation: A new bioelectronics approach to treat rheumatoid arthritis?
نویسندگان
چکیده
منابع مشابه
Targeting plasticity with vagus nerve stimulation to treat neurological disease.
Pathological neural activity in a variety of neurological disorders could be treated by directing plasticity to specifically renormalize aberrant neural circuits, thereby restoring normal function. Brief bursts of acetylcholine and norepinephrine can enhance the neural plasticity associated with coincident events. Vagus nerve stimulation (VNS) represents a safe and effective means to trigger th...
متن کاملA New Approach to Rheumatoid Arthritis: Treating Inflammation with Computerized Nerve Stimulation
Doctors currently treat rheumatoid arthritis, a crippling autoimmune disease, with an arsenal of drugs that, while often effective, can have serious side effects. Authors Ulf Andersson and Kevin J. Tracey describe a circuit between the immune system and the nervous system that enabled development of an implanted nerve stimulator to treat the disorder, now being tested by a patient in Bosnia. If...
متن کاملVagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis.
Rheumatoid arthritis (RA) is a heterogeneous, prevalent, chronic autoimmune disease characterized by painful swollen joints and significant disabilities. Symptomatic relief can be achieved in up to 50% of patients using biological agents that inhibit tumor necrosis factor (TNF) or other mechanisms of action, but there are no universally effective therapies. Recent advances in basic and preclini...
متن کاملVagus nerve stimulation therapy
Over the past 5 years, and especially within the last year, there has been a rapid expansion of vagus nerve stimulation (VNS)-related preclinical research, as well as clinical studies in indications other than epilepsy. The research advances in understanding VNS are occurring in the midst of a blossoming of other forms of therapeutic brain stimulation, such as electroconvulsive therapy (ECT), t...
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ژورنال
عنوان ژورنال: Best Practice & Research Clinical Rheumatology
سال: 2014
ISSN: 1521-6942
DOI: 10.1016/j.berh.2014.10.015